Title: The Chemical Composition and Applications of ADB-PINACA: A Comprehensive Review
Introduction
ADB-PINACA (Methyl-2-[1-(4-fluorobenzyl)-1H-indazole-3-carboxamido]-3-methylbutanoate) is a synthetic cannabinoid receptor agonist that has gained significant attention in recent years due to its increasing use as a recreational drug. This compound is a member of the indazole carboxamide family, which is a class of synthetic cannabinoids that are designed to mimic the effects of natural cannabinoids found in the cannabis plant. This review aims to provide a comprehensive overview of the chemical composition and applications of ADB-PINACA. https://bbgate.com/media/adb-pinaca-synthesis.93/
Chemical Composition
ADB-PINACA is a complex organic compound that consists of several functional groups, including a carboxamide group, an indazole ring, a benzyl group, and a butanoate group. The compound has a molecular formula of C22H27FN3O4, with a molecular weight of 413.46 g/mol. The presence of a fluorine atom in the benzyl group makes ADB-PINACA a halogenated compound, which can affect its pharmacological properties and metabolism.
The chemical synthesis of ADB-PINACA involves several steps, including the preparation of the indazole ring, the introduction of the carboxamide group, and the addition of the butanoate and benzyl groups. The synthesis process requires careful control of reaction conditions, such as temperature and pH, to ensure the formation of the desired product. The final product is typically purified by recrystallization or chromatography before being used for further studies.
Pharmacological Properties
ADB-PINACA exerts its pharmacological effects by binding to cannabinoid receptors in the brain, specifically CB1 and CB2 receptors. These receptors are involved in various physiological processes, such as pain perception, appetite regulation, and memory formation. The binding of ADB-PINACA to these receptors can lead to a range of effects, including altered perception, sedation, and psychoactive effects. The potency of ADB-PINACA is reported to be significantly higher than that of natural cannabinoids, such as THC, which can lead to a higher risk of adverse effects.
Applications
The high potency and selectivity of ADB-PINACA make it a valuable tool for research in the field of medicinal chemistry and pharmacology. The compound can be used to study the structure-activity relationships of cannabinoid receptors and the development of novel therapeutic agents for various diseases, such as pain, inflammation, and neurodegenerative disorders.
However, the recreational use of ADB-PINACA and other synthetic cannabinoids has raised significant public health concerns due to their potential for abuse and adverse effects. The compound has been linked to several cases of severe intoxication, including seizures, cardiac arrest, and death. The unregulated nature of the synthesis and distribution of ADB-PINACA makes it difficult to ensure its quality and safety, which further increases the risk of adverse effects.
Conclusion
In conclusion, ADB-PINACA is a complex synthetic cannabinoid with a unique chemical composition and pharmacological properties. Its high potency and selectivity make it a valuable tool for research, but its recreational use poses significant public health concerns. Further studies are needed to fully understand the potential benefits and risks of ADB-PINACA and other synthetic cannabinoids, and to develop effective strategies for their regulation and control.
CAS 28578-16-7: Unveiling the Mysteries of an Enigmatic Compound In the vast world of chemical compounds, where numbers and formulas dance around like characters in an intricate play, there... Далі...
Exploring the Enigmatic: Unraveling the Mysteries of CAS 28578-16-7 Introduction: A Journey into the Unknown In the vast realm of chemical compounds, there exist entities that beckon... Далі...
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як Kurt Lambert (2024-03-08)
З приводу Re: Directory of onion sites in darkweb | deep web links deep web access
Title: The Chemical Composition and Applications of ADB-PINACA: A Comprehensive Review
Introduction
ADB-PINACA (Methyl-2-[1-(4-fluorobenzyl)-1H-indazole-3-carboxamido]-3-methylbutanoate) is a synthetic cannabinoid receptor agonist that has gained significant attention in recent years due to its increasing use as a recreational drug. This compound is a member of the indazole carboxamide family, which is a class of synthetic cannabinoids that are designed to mimic the effects of natural cannabinoids found in the cannabis plant. This review aims to provide a comprehensive overview of the chemical composition and applications of ADB-PINACA. https://bbgate.com/media/adb-pinaca-synthesis.93/
Chemical Composition
ADB-PINACA is a complex organic compound that consists of several functional groups, including a carboxamide group, an indazole ring, a benzyl group, and a butanoate group. The compound has a molecular formula of C22H27FN3O4, with a molecular weight of 413.46 g/mol. The presence of a fluorine atom in the benzyl group makes ADB-PINACA a halogenated compound, which can affect its pharmacological properties and metabolism.
The chemical synthesis of ADB-PINACA involves several steps, including the preparation of the indazole ring, the introduction of the carboxamide group, and the addition of the butanoate and benzyl groups. The synthesis process requires careful control of reaction conditions, such as temperature and pH, to ensure the formation of the desired product. The final product is typically purified by recrystallization or chromatography before being used for further studies.
Pharmacological Properties
ADB-PINACA exerts its pharmacological effects by binding to cannabinoid receptors in the brain, specifically CB1 and CB2 receptors. These receptors are involved in various physiological processes, such as pain perception, appetite regulation, and memory formation. The binding of ADB-PINACA to these receptors can lead to a range of effects, including altered perception, sedation, and psychoactive effects. The potency of ADB-PINACA is reported to be significantly higher than that of natural cannabinoids, such as THC, which can lead to a higher risk of adverse effects.
Applications
The high potency and selectivity of ADB-PINACA make it a valuable tool for research in the field of medicinal chemistry and pharmacology. The compound can be used to study the structure-activity relationships of cannabinoid receptors and the development of novel therapeutic agents for various diseases, such as pain, inflammation, and neurodegenerative disorders.
However, the recreational use of ADB-PINACA and other synthetic cannabinoids has raised significant public health concerns due to their potential for abuse and adverse effects. The compound has been linked to several cases of severe intoxication, including seizures, cardiac arrest, and death. The unregulated nature of the synthesis and distribution of ADB-PINACA makes it difficult to ensure its quality and safety, which further increases the risk of adverse effects.
Conclusion
In conclusion, ADB-PINACA is a complex synthetic cannabinoid with a unique chemical composition and pharmacological properties. Its high potency and selectivity make it a valuable tool for research, but its recreational use poses significant public health concerns. Further studies are needed to fully understand the potential benefits and risks of ADB-PINACA and other synthetic cannabinoids, and to develop effective strategies for their regulation and control.
Відповіді
Re: Re: Re: Directory of onion sites in darkweb | deep web links deep web access
як Kurt Lambert (2024-04-07)
CAS 28578-16-7: Unveiling the Mysteries of an Enigmatic Compound In the vast world of chemical compounds, where numbers and formulas dance around like characters in an intricate play, there... Далі...
Re: Re: Re: Directory of onion sites in darkweb | deep web links deep web access
як Kurt Lambert (2024-04-09)
Exploring the Enigmatic: Unraveling the Mysteries of CAS 28578-16-7 Introduction: A Journey into the Unknown In the vast realm of chemical compounds, there exist entities that beckon... Далі...