Title: Synthesis, Chemical Composition, and Applications of α-Pyrrolidinopentiophenone (α-PVP)
Introduction
The demand for novel psychoactive substances (NPS) has been increasing over the past decade, with α-Pyrrolidinopentiophenone (α-PVP) being one of the most popular. α-PVP, also known as Flakka or Gravel, is a synthetic cathinone that has been linked to numerous health and social issues worldwide. This article aims to provide a comprehensive overview of the synthesis, chemical composition, and applications of α-PVP.
α-PVP was first synthesized in the 1960s by a team of chemists led by H. J. Ringold. It is a derivative of pyrovalerone, a stimulant that was widely used in the 1960s and 1970s as an appetite suppressant. α-PVP is synthesized through a series of chemical reactions involving the condensation of 1-phenyl-2-pyrrolidin-1-ylpentan-1-one with various reagents, including hydrochloric acid, sodium hydroxide, and acetic acid. The synthesis of α-PVP requires advanced knowledge of organic chemistry and access to specialized laboratory equipment.
Chemical Composition of α-PVP
α-PVP is a white or off-white crystalline powder that is soluble in water and alcohol. Its chemical formula is C15H21NO and its molecular weight is 231.33 g/mol. α-PVP is a chiral compound, meaning that it has a non-superimposable mirror image. Its stereochemistry plays a significant role in its pharmacological activity. α-PVP is a potent NPS that acts as a stimulant and hallucinogen. It is structurally similar to other cathinones, such as methcathinone and mephedrone, but its effects are more potent and longer-lasting.
Applications of α-PVP
α-PVP has been used for various purposes, including recreational, therapeutic, and research applications. Its stimulant effects make it a popular drug of abuse, and it has been linked to numerous health and social issues worldwide. α-PVP use can cause a range of adverse effects, including increased heart rate, blood pressure, and body temperature, as well as agitation, hallucinations, and paranoia. α-PVP has also been linked to several deaths due to its potency and long-lasting effects.
Despite its negative consequences, α-PVP has some potential therapeutic applications. Its stimulant effects make it a potential treatment for narcolepsy, a neurological disorder characterized by excessive daytime sleepiness. α-PVP has also been shown to have analgesic effects, making it a potential alternative to opioid painkillers. However, more research is needed to determine the safety and efficacy of α-PVP for these purposes.
α-PVP is also a valuable research tool for studying the mechanisms of addiction and drug abuse. Its potent stimulant effects make it an ideal model for studying the neurobiology of addiction. Researchers can use α-PVP to investigate the neural pathways involved in drug reward and reinforcement, as well as the molecular mechanisms underlying drug tolerance and dependence.
Conclusion
α-PVP is a potent NPS with a wide range of applications. Its synthesis, chemical composition, and pharmacological activity make it a valuable tool for researchers and clinicians alike. However, its potential for abuse and negative health consequences cannot be ignored. It is essential to regulate the production and distribution of α-PVP to prevent its misuse and protect public health. Further research is needed to fully understand the potential therapeutic applications of α-PVP and to develop effective strategies for preventing and treating its abuse.
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З приводу Re: Directory of onion sites in darkweb | deep web links deep web access
Title: Synthesis, Chemical Composition, and Applications of α-Pyrrolidinopentiophenone (α-PVP)
Introduction
The demand for novel psychoactive substances (NPS) has been increasing over the past decade, with α-Pyrrolidinopentiophenone (α-PVP) being one of the most popular. α-PVP, also known as Flakka or Gravel, is a synthetic cathinone that has been linked to numerous health and social issues worldwide. This article aims to provide a comprehensive overview of the synthesis, chemical composition, and applications of α-PVP.
https://bbgate.com/tags/a-pvp/
Synthesis of α-PVP
α-PVP was first synthesized in the 1960s by a team of chemists led by H. J. Ringold. It is a derivative of pyrovalerone, a stimulant that was widely used in the 1960s and 1970s as an appetite suppressant. α-PVP is synthesized through a series of chemical reactions involving the condensation of 1-phenyl-2-pyrrolidin-1-ylpentan-1-one with various reagents, including hydrochloric acid, sodium hydroxide, and acetic acid. The synthesis of α-PVP requires advanced knowledge of organic chemistry and access to specialized laboratory equipment.
Chemical Composition of α-PVP
α-PVP is a white or off-white crystalline powder that is soluble in water and alcohol. Its chemical formula is C15H21NO and its molecular weight is 231.33 g/mol. α-PVP is a chiral compound, meaning that it has a non-superimposable mirror image. Its stereochemistry plays a significant role in its pharmacological activity. α-PVP is a potent NPS that acts as a stimulant and hallucinogen. It is structurally similar to other cathinones, such as methcathinone and mephedrone, but its effects are more potent and longer-lasting.
Applications of α-PVP
α-PVP has been used for various purposes, including recreational, therapeutic, and research applications. Its stimulant effects make it a popular drug of abuse, and it has been linked to numerous health and social issues worldwide. α-PVP use can cause a range of adverse effects, including increased heart rate, blood pressure, and body temperature, as well as agitation, hallucinations, and paranoia. α-PVP has also been linked to several deaths due to its potency and long-lasting effects.
Despite its negative consequences, α-PVP has some potential therapeutic applications. Its stimulant effects make it a potential treatment for narcolepsy, a neurological disorder characterized by excessive daytime sleepiness. α-PVP has also been shown to have analgesic effects, making it a potential alternative to opioid painkillers. However, more research is needed to determine the safety and efficacy of α-PVP for these purposes.
α-PVP is also a valuable research tool for studying the mechanisms of addiction and drug abuse. Its potent stimulant effects make it an ideal model for studying the neurobiology of addiction. Researchers can use α-PVP to investigate the neural pathways involved in drug reward and reinforcement, as well as the molecular mechanisms underlying drug tolerance and dependence.
Conclusion
α-PVP is a potent NPS with a wide range of applications. Its synthesis, chemical composition, and pharmacological activity make it a valuable tool for researchers and clinicians alike. However, its potential for abuse and negative health consequences cannot be ignored. It is essential to regulate the production and distribution of α-PVP to prevent its misuse and protect public health. Further research is needed to fully understand the potential therapeutic applications of α-PVP and to develop effective strategies for preventing and treating its abuse.
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Re: Re: Re: Directory of onion sites in darkweb | deep web links deep web access
як Kurt Lambert (2024-04-10)
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Re: Re: Re: Directory of onion sites in darkweb | deep web links deep web access
як Kurt Lambert (2024-04-10)
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